Our Team
At CellFe Labs, we're a small but dynamic team of researchers embarking on an exciting journey in biomanufacturing. Though our lab is only a year old, we're already making significant strides in synthetic biology, fermentation, and cell-free systems. Each of us brings unique expertise to the table, all with the shared goal of developing sustainable solutions. We’re eager to grow and welcome dedicated and motivated researchers to join us. Currently, we have two open Ph.D. positions for those ready to help push the boundaries of what’s possible in biotechnology. We’re united by our passion for science and innovation, and we collaborate closely to push the boundaries of what’s possible in our field.
Meet the Principal Investigator
Assistant Professor, Karen M Swindler Department of Chemical and Biological Engineering
I am a microbiologist by training and a biological engineer by practice, with a strong foundation in both disciplines. My academic journey began in India, where I earned my B.S. and M.S. in Microbiology from Panjab University. Driven by a passion for integrating biology with engineering, I pursued a Ph.D. in Chemical and Biological Engineering at SD Mines, USA, where I now lead the CellFe Lab. At CellFe Labs, we are at the forefront of biomanufacturing, blending traditional fermentation, synthetic biology, and pioneering cell-free biomanufacturing to transform unconventional feedstocks—such as agricultural residues and plastics—into high-value biopolymers and biochemicals. Beyond the lab, I am deeply committed to mentoring the next generation of scientific leaders. I encourage my students to think beyond the conventional and empower them to turn groundbreaking research into real-world applications. In my courses, CBE 217: ‘Chemical Engineering Material Balances’ and CBE 741: ‘Microbial and Enzymatic Processes,’ I draw from my research to create an integrated learning experience that deepens students' understanding of how biology and engineering intersect to drive innovation.
Team Members
Kritika Thakur Graduate Research Assistant in CellFe Labs since January 2024
Hello! I am a graduate student in the Chemical and Biomolecular Engineering department at SD Mines. I joined CellFe Lab in January 2024 and am currently working on an NSF Future Manufacturing Project to synthesize Polyhydroxyalkanoates (PHAs) from Corn Stover using Cell-Free Biomanufacturing. For this project, I am harnessing the capabilities of a thermophilic non-model microbe, Geobacillus sp. cnambio1, to develop enzyme systems that operate outside of living cells. My skill set includes enzyme engineering, biocatalysis, and advanced techniques for biopolymer synthesis.
Kelly M. Sutko
Graduate Research Assistant in CellFe Labs since January 2024 (also "Entrepreneur")
Hello! I am a graduate student working on an innovative project that centers around the Exopolysaccharide (EPS) produced by a thermophilic strain of Geobacillus sp. WSUCF1. My research is focused on altering the hydrophobicity of this EPS to enhance its compatibility with 3D printing technologies. The goal is to develop materials that can effectively encapsulate microbial biofertilizers, contributing to more sustainable agricultural practices. This research is a key component of the RII Track-2 FEC: Center for Climate Conscious Agricultural Technologies (CCAT), under Abstract #2316502.
Antonia Gibbs (Block)
Undergraduate Student Researcher in CellFe Labs since August 2023
Hello! I am Junior chemical engineering student at the South Dakota School of Mines and Technology, researching with Cell Fe Labs and focused on developing biodegradable Polyhydroxyalkanoates (PHA) films for commercial agricultural use. My work involves testing the biodegradability of PHA and assessing its impact on plant and soil health. To support this research, I helped establish a small greenhouse unit and a growth chamber within the CBE labs. This project is a critical part of the RII Track-2 FEC: BioWRAP Project, under Abstract #2119753.